Inflammatory lung diseases in children

​Childhood respiratory diseases represent an important cause of morbidity and mortality. ​They are characterized by the existence of local inflammation that must be eliminated in order to maintain potential growth and avoid decreasing the pulmonary capacity as well as developing chronic respiratory insufficiency. Many lung disorders such as asthma, chronic obstructive pulmonary diseases (COPD), cystic fibrosis, and pulmonary fibrosis, are characterized by an inappropriate and chronic inflammatory response of the respiratory system.  The objectives of the program developed with all the expertise of I2B research structure are to: (i) improve understanding of the mechanisms that contribute to dysregulation of the pulmonary immune system and the associated inflammatory response; (ii) identify specific markers of pulmonary inflammation; (iii) develop appropriate therapeutic strategies.