Internal Medecine Department (Tenon)

National reference center for inflammatory amyloidosis and familial Mediterranean fever


​The internal medicine department of CHU Tenon is mainly devoted to general internal medicine and to some rare diseases: auto-inflammatory diseases, amyloidosis and sickle cell diseases. We coordinate the National reference center for Rare systemic and auto-immune disorders “Amyloidosis of inflammatory origin and familial Mediterranean fever” and are associated with the National reference center for “Major sickle cell disease syndromes”. We are in charge of a cohort of around 300 patients with auto-inflammatory diseases, mainly familial mediterranean fever, and of a cohort of 700 patients with sickle cell disease.

We have a sustained activity in advice for patients with suspected auto-inflammatory amyloidosis.

In patients with undetermined amyloidosis, we work at establishing the true nature of the disease collecting clinical, immunohistochemical and genetic data.

We have been working with Serge Amselem’s team at discovering new genes involved in families with an autoinflammatory phenotype.

We also work at elucidating the genetic basis of the susceptibility to AA amyloidosis in patients with familial mediterranean fever and other inflammatory disorders.

​​Team 1- Auto-inflammatory diseases and amyloidosis: Gilles Grateau, Katia Stankovic and Sophie Georgin-Lavialle

Team 2- Sickle cell diseases: François Lionnet, Katia Stankovic, Anne Léon​

Fields of interest

Auto-inflammatory diseases, Amyloidosis, Sickle cell disease, Clinics, Genetics, Inflammation, Renal involvement, Metabolism

Affiliations AP-HP logo



Contact info

Address: Internal Medicine, Hôpital Tenon, 4 rue de la Chine
City: Paris
Postal code: 75970

Top Publications